The role of the microenvironment in tumor immune surveillance

نویسندگان

  • Oluwadayo Oluwadara
  • Luca Giacomelli
  • Xenia Brant
  • Russell Christensen
  • Raisa Avezova
  • George Kossan
  • Francesco Chiappelli
چکیده

The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O'Shea & Paul, 2010 [4]). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2011